首页 | 本学科首页   官方微博 | 高级检索  
文章检索
  按 检索   检索词:      
出版年份:   被引次数:   他引次数: 提示:输入*表示无穷大
  收费全文   4957篇
  免费   59篇
  国内免费   85篇
系统科学   43篇
丛书文集   101篇
教育与普及   72篇
理论与方法论   8篇
现状及发展   1977篇
研究方法   200篇
综合类   2688篇
自然研究   12篇
  2022年   39篇
  2021年   49篇
  2014年   45篇
  2012年   88篇
  2011年   114篇
  2010年   53篇
  2009年   132篇
  2008年   105篇
  2007年   140篇
  2006年   94篇
  2005年   132篇
  2004年   144篇
  2003年   92篇
  2002年   96篇
  2001年   231篇
  2000年   204篇
  1999年   167篇
  1998年   56篇
  1997年   57篇
  1996年   43篇
  1995年   49篇
  1992年   105篇
  1991年   102篇
  1990年   100篇
  1989年   77篇
  1988年   84篇
  1987年   85篇
  1986年   59篇
  1985年   98篇
  1984年   82篇
  1983年   62篇
  1982年   65篇
  1981年   59篇
  1980年   75篇
  1979年   146篇
  1978年   134篇
  1977年   107篇
  1976年   79篇
  1975年   73篇
  1974年   98篇
  1973年   103篇
  1972年   89篇
  1971年   111篇
  1970年   100篇
  1969年   96篇
  1968年   95篇
  1967年   87篇
  1966年   86篇
  1965年   58篇
  1958年   41篇
排序方式: 共有5101条查询结果,搜索用时 62 毫秒
981.
具变号位势的二阶离散哈密顿系统的周期解   总被引:1,自引:0,他引:1  
利用山路引理研究一类具变号位势的二阶离散Hamilton系统的周期解的存在性.首先将该类离散Hamilton系统的周期解的存在性转化为适当函数空间上对应泛函的临界点的存在性,然后用山路引理证得临界点的存在性,得到一个存在性定理.  相似文献   
982.
离散杆战斗部中隔板形状研究   总被引:1,自引:0,他引:1  
目的 研究空空导弹离散杆战斗部中隔板的形状;方法 对3 种隔板的形状进行了研究,并通过数值方法对隔板的效能进行了计算;结果 给出了3 种隔板的最小装药量、隔板在装药中间部位径向的最大尺寸、冲击波在隔板中传播时间的计算模型,并得到了3种隔板的内形方程; 结论 通过数值结果验证折线形隔板对杆条破裂程度的作用远优于其他两种形状的隔板;  相似文献   
983.
A solution containing nanometer-sized pure gold particles was prepared with the hydrolysisreduction method. As observed under the electron microscope, the gold particles were as large as 2–20 nm in size. Different kinds of mineral and rock were put into the solution and the experimental result showed that the nanometer-sized gold particles are obviously adsorbed on sulfide minerals, native copper and carbonaceous rocks. This experimental result is consistent with the actual geological observation. On this basis a better explanation is presented of the genesis of the Carlin-type gold deposits.  相似文献   
984.
湖南山丘区景观生态建设的基本问题   总被引:3,自引:0,他引:3  
湖南山丘区景观生态系统退化严重,成为山丘区及全省社会经济可持续发 障碍因素,开展山丘景观生态建设,既有助于植被的恢复,土地肥力的提高和生态环境质量的改善,也是山丘区域脱贫致富的重要途径,山区景观生态建设必须遵循适应自然,控制共生,组织整合和功能优化和等基本原则,建立包括农林结合林结合、农林特结合等多种具体形式的农林业系统。  相似文献   
985.
Bid-deficient mice are resistant to Fas-induced hepatocellular apoptosis.   总被引:74,自引:0,他引:74  
X M Yin  K Wang  A Gross  Y Zhao  S Zinkel  B Klocke  K A Roth  S J Korsmeyer 《Nature》1999,400(6747):886-891
The protein Bid is a participant in the pathway that leads to cell death (apoptosis), mediating the release of cytochrome c from mitochondria in response to signals from 'death' receptors known as TNFR1/Fas on the cell surface. It is a member of the proapoptotic Bcd-2 family and is activated as a result of its cleavage by caspase 8, one of a family of proteolytic cell-death proteins. To investigate the role of Bid in vivo, we have generated mice deficient for Bid. We find that when these mice are injected with an antibody directed against Fas, they nearly all survive, whereas wild-type mice die from hepatocellular apoptosis and haemorrhagic necrosis. About half of the Bid-deficient animals had no apparent liver injury and showed no evidence of activation of the effector caspases 3 and 7, although the initiator caspase 8 had been activated. Other Bid-deficient mice survived with only moderate damage: all three caspases (8 and 37) were activated but their cell nuclei were intact and no mitochondrial cytochrome c was released. We also investigated the effects of Bid deficiency in cultured cells treated with anti-Fas antibody (hepatocytes and thymocytes) or with TNFalpha. (fibroblasts). In these Bid-/- cells, mitochondrial dysfunction was delayed, cytochrome c was not released, effector caspase activity was reduced and the cleavage of apoptosis substrates was altered. This loss-of-function model indicates that Bid is a critical substrate in vivo for signalling by death-receptor agonists, which mediates a mitochondrial amplification loop that is essential for the apoptosis of selected cells.  相似文献   
986.
A new method is described for measuring motions of protein domains in their native environment on the physiological timescale. Pairs of cysteines are introduced into the domain at sites chosen from its static structure and are crosslinked by a bifunctional rhodamine. Domain orientation in a reconstituted macromolecular complex is determined by combining fluorescence polarization data from a small number of such labelled cysteine pairs. This approach bridges the gap between in vitro studies of protein structure and cellular studies of protein function and is used here to measure the tilt and twist of the myosin light-chain domain with respect to actin filaments in single muscle cells. The results reveal the structural basis for the lever-arm action of the light-chain domain of the myosin motor during force generation in muscle.  相似文献   
987.
提出塑性损伤变量的定义,它由反映微空隙群的材料相对体积膨胀来表征.从理论上导出了塑性损伤变量Dp 与经典连续损伤力学中弹性损伤变量De= 1- E/E 之间的关系.根据此关系,用实验方法确定了聚合物材料HIPS在纵向拉伸过程中损伤变量的扩展  相似文献   
988.
对聚合物材料HIPS进行了系统的变形-损伤试验研究.用提出的弹塑性损伤变量与关系分析了Ⅰ型裂纹端部的损伤场,给出了损伤场内非线性纵向应变分布与纵向应力分布.给出的损伤分析方法为进一步研究裂纹在损伤区内的稳定扩展奠定了新的基础  相似文献   
989.
This paper studies on fabrics suitable for child patients'garment in the hospital environment in Hong Kong,China.Subjective measurement was carried out by questionnaire survey to consult medical staff on hospital requirement about fabric criteria for child patients' garment. On the other hand, objective measurement was conducted by performing laboratory tests on fabrics,which were sourced from commercial fabric market. Both measurements are evaluated according to the results on those fabric criteria in order to determine the most suitable kind of fabric for the end purpose. As a result of the comparison, it was found that T/C 1 scores the highest index. Therefore, it will be suggested for manufacturing child patients' garment to evaluate the fabric suitability to meet the wearers' requirement through hospital trial.  相似文献   
990.
This paper described the physical behaviour of three types of denim cloths produced from rotor yarn, ring yarn and modified rotor yarn (prepared by adding conventional twist to rotor yarn) respectively. Experimental work showed that denim cloth produced from the modified rotor yarn has superior properties over conventional rotor yarn in terms of surface texture and appearance,tearing strength and resistance to abrasion.  相似文献   
设为首页 | 免责声明 | 关于勤云 | 加入收藏

Copyright©北京勤云科技发展有限公司  京ICP备09084417号